Current Research Studies

Current Research Studies

Research studies at the Research Institute at Lindner Center of HOPE are currently being conducted for Bipolar Disorder, Major Depression and Eating Disorders.

The Research Institute at Lindner Center of HOPE conducts research regarding the biological causes and treatments for mood and eating disorders. Currently Dr. Susan McElroy is recruiting people for studies on bipolar disorder (also known as manic depression), major depression, eating disorders (binge eating disorder), and smoking cessation.


For more information about the Research Institute, contact (513) 536-0716 or click here.


If you would like to fill out a short pre-screen questionnaire for one of our research studies/paid research studies in Cincinnati, please click below:

Weight loss in stable bipolar disorder

Depression study using non-invasive spinal stimulation

MYDAYIS®  for Bipolar Depression

Post-Traumatic Stress Disorder medication study

Obesity study:  the role of the circadian system in binge eating disorder

Diagnosed With Bipolar Disorder And Overweight?

What:
The purpose of this placebo controlled research study is to gather information about the effects of investigational medication on weight loss in individuals with stable Bipolar Disorder.

Who:
18-65 years old men and women diagnosed with Bipolar Disorder who are obese or overweight and interested in weight loss. Must be on a stable regimen of medication for Bipolar Disorder for at least 3 months.

Pay:
Study-related evaluations, tests and medication without charge. Eligible participants will be compensated $50 per visit for their time and travel.

Details:
If you would like to fill out a short pre-screen questionnaire for our weight loss in stable bipolar disorder study, please click here.

For more information about the Research Institute, contact (513) 536-0710 or email Anna Guerdjikova at Anna.Guerdjikova@LindnerCenter.org


Bipolar Disorder Depression Study

Do You Have Bipolar Disorder and Are Currently Depressed?

What:
The purpose of this research is to see if Mydayis will improve mood in patients with bipolar disorder and currently suffering from depression.  Participants will be randomly assigned to take Mydayis or a placebo (a fake pill with no active ingredient).

Who:
Adults, age 18-55 who are currently experiencing depression and diagnosed with bipolar disorder.  Participants must be on a mood stabilizer prescribed by their doctor.

Pay:
Eligible participants will be compensated up to $390 for their time, effort and travel.

Details:
For more information, please contact us at 513-536-0707 or fill out a pre-screen questionnaire here

For more information about the Research Institute, contact (513) 536-0707 or email Brian Martens at Brian.Martens@lindnercenter.org.

Diagnosed With Bipolar Disorder And Overweight?

What:
The purpose of this placebo controlled research study is to gather information about the effects of investigational medication on weight loss in individuals with stable Bipolar Disorder.

Who:
18-65 years old men and women diagnosed with Bipolar Disorder who are obese or overweight and interested in weight loss. Must be on a stable regimen of medication for Bipolar Disorder for at least 3 months.

Pay:
Study-related evaluations, tests and medication without charge. Eligible participants will be compensated $50 per visit for their time and travel.

Details:
If you would like to fill out a short pre-screen questionnaire for our weight loss in stable bipolar disorder study, please click here.

For more information about the Research Institute, contact (513) 536-0710 or email Anna Guerdjikova at Anna.Guerdjikova@LindnerCenter.org


Participants with Obesity and Binge Eating Disorder

What:
The purpose of this study is to learn more about binge eating disorder (BED).  Participants will be asked to come in for 8 visits over approximately 6 weeks.  Participants will be randomly assigned to a study intervention or sham/placebo in the final four weeks of the study.

Who:
Adults age 18-50, currently with obesity and experiencing binge eating disorder symptoms.

Pay:
Eligible participants will be compensated up to $440 for their time and travel.

Details:
For more information, contact Brian or George at (513) 536-0707 or fill out a pre-screen questionnaire here.

Non-invasive Spinal Stimulation for the Treatment of Major Depression

What:
The purpose of this study is to evaluate whether the use of a small electrical current applied through the skin is useful and safe in the treatment of adults diagnosed with major depression. Participation will last approximately 8 weeks and involve visits to the research center three times per week.

Who:
Adults ages 18–55 who are currently moderately depressed for at least 1 month. Not currently on medication treatment for depression.

Pay:
Eligible participants will be compensated up to $250 for their time and travel.

Details:
For more information, contact Brian or George at 513-536-0707.

If you would like to fill out a short pre-screen questionnaire for our depression study, please click here.


Investigational medication study for adults with depression

What:
Do you have depression? A clinical research study is now enrolling eligible adults.
The purpose of this study is to evaluate the safety and effectiveness of an investigational medicine in people with depression.

Who:
You may be eligible to participate if you:

  • are 18–74 years of age
  • have been diagnosed with depression
  • have taken antidepressants in the past that did not work well for you
  • are currently taking an antidepressant medication but still have symptoms of depression.

Pay:
Qualified patients may receive study-related medical care and investigational study medication at no cost. The study will not pay for other medical care or current medication(s) needed to support your daily health care routine.

Details:
If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. You can expect to be in the study for up to 10–12 weeks. If you stop the study early, you will be asked to complete the early withdrawal visit and come to the study center for additional assessments. In some cases, you may have the option to continue participation for up to an additional 52 weeks.

To learn more about this clinical research study, please contact Brian or George at 513-536-0707 or email at brian.martens@lindnercenter.org

To see a study pamphlet, click here.

Post-Traumatic Stress Disorder Study

IRB Committee:
This study has been reviewed and approved by Advarra Institutional Review Board.

What:
The Lindner Center of HOPE is currently enrolling subjects for a Post-Traumatic Stress Disorder (PTSD) research study.

Who:
Adults 18 to 65 years old, who have been diagnosed with PTSD and are currently experiencing symptoms.

Reimbursements:
Participants may be reimbursed for study-related travel expenses.

If you would like to fill out a short pre-screen questionnaire for our post-traumatic stress disorder study, please click here.

Thank you for your interest in the study. After you complete this confidential form someone will contact you via phone or email to let you know if you are a potential candidate for the study.

You can also reach us by phone at 513-536-0707, Monday – Friday, between 8:30 AM and 5:00 PM. . All information will be kept confidential in accordance with our Privacy Policy (Link). You will be able to opt out at any point and your information will be deleted from the system.

Obesity Study

Participants with obesity

The purpose of this study is to learn more about the role of the circadian system in binge eating disorder (BED).  Participants will be asked to come in for 4 visits over approximately 2 weeks.

Who:
Adults age 18-50, currently with obesity that do not have current or lifetime history of binge eating disorder or bulimia nervosa.

Pay:
Eligible participants will be compensated up to $215 for their time and travel.

Details:
For more information, contact Brian or George at (513) 536-0707 or fill out a pre-screen questionnaire here.