Current Clinical Trials
Research studies at the Research Institute at Lindner Center of HOPE are currently being conducted for Bipolar Disorder, Major Depression and Eating Disorders.
The Research Institute at Lindner Center of HOPE conducts research regarding the biological causes and treatments for mood and eating disorders. Currently Dr. Susan McElroy is recruiting people for studies on bipolar disorder (also known as manic depression), major depression, eating disorders (binge eating disorder), and smoking cessation.
For more information about the Research Institute, contact (513) 536-0716 or click here.
Currently Dr. Susan McElroy is recruiting people for studies on bipolar disorder (also known as manic depression), major depression, eating disorders (binge eating disorder), and smoking cessation.
If you would like to fill out a short pre-screen questionnaire for our bipolar study, please click here.
Currently suffering from bipolar disorder and depression?
What:
The purpose of the research study is to investigate whether proteins in the bloodstream, measured with a blood test, can determine if a depressed person has bipolar I disorder, bipolar II disorder, or major depressive disorder.
Who:
Adults ages 18-70 who have bipolar I or II disorder and are currently depressed.
Pay:
Participant may receive up to $350 for time and travel.
Details
For more information, call (513) 536-0707. To complete a pre-screen questionnaire, please visit LCOH.info. Located in Mason, OH
Are your Bipolar medications working well, but you’re struggling with being overweight?
What :
The Lindner Center of HOPE is conducting a clinical trial with an FDA-approved antiobesity medication, seeking patients with bipolar disorder who are interested in losing weight.
Who :
Overweight or obese adults, 18-65yrs of age inclusive, who have been diagnosed with and are on stable medication regimen for their bipolar disorder
Pay:
Participants receive $50/visit. Nutritional & lifestyle counseling, lab and diagnostic tests provided free of charge.
For more information, please call (513) 536-0710
For more information about the Research Institute, contact (513) 536-0716 or email Brian Martens at brian.martens@lindnercenter.org.
Do you want to quit smoking?
Lindner Center of HOPE is conducting a clinical trial of a non‐invasive, investigational medical device, Deep Transcranial Magnetic Stimulation, that may help people to quit smoking.
To be eligible you must:
- Be between the ages of 22– 70 years old
- Have smoked at least 10 cigarettes a day for over a year
- Want to quit smoking
All qualified participants will receive study related exams, lab work and treatments at no cost.
Enrolled participants will receive compensation for time and travel.
For more information, please call Anna at (513) 536-0721.
Taking depression medication but still feeling depressed?
What : Rapastinel/ RAP-MD
The Lindner Center of HOPE is conducting a clinical trial of Rapastinel, a novel experimental drug, to be used in addition to conventional medication in the treatment of Major Depression. Rapastinel has received FDA designation as a “breakthrough therapy” with individuals whose symptoms haven’t experienced significant improvement from their current antidepressant.
Who:
Adults 18-65yrs of age inclusive who are currently depressed and are taking an antidepressant medication with not sufficient improvement
Pay:
Participants receive $75/visit and are expected to come for 12 study visits. Lab and diagnostic tests provided free of charge
For more information, please call (513) 536-0710
Non-invasive Spinal Stimulation for the Treatment of Major Depression
What
The purpose of this study is to evaluate whether the use of a small electrical current applied through the skin is useful and safe in the treatment of adults diagnosed with major
depression. Participation will last approximately 8 weeks and involve visits to the research center three times per week.
Who
Adults ages 18–50 who are currently moderately depressed for at least 1 month. Not currently on medication treatment for depression.
Pay
Eligible participants will be compensated up to $250 for their time and travel.
Details
For more information, contact Brian or George at 513-536-0707 or visit www.LCOH.info and fill out a pre-screen questionnaire. Located at the Lindner Center of HOPE in Mason, Ohio.
If you would like to fill out a short pre-screen questionnaire for our depression study, please click here.
If interested in participating in the trial, contact 513-536-0710.
Pediatric Tourette Syndrome (T-Force Gold Study)
What:
The primary purpose of this clinical research study is to determine the safety, tolerability, and effectiveness of an investigational medication for Tourette syndrome in children. An investigational medication is one that is not approved by the US Food and Drug Administration (FDA).
Who:
Boys and girls aged 6–17 years. Have a diagnosis of Tourette syndrome and symptoms that impair school, occupational, and/or social function. Are in good general health, as determined by medical history, physical examination, and laboratory tests.
Study schedule:
Attend a Screening Visit to determine eligibility. Participate in the clinical research study for up to 18 weeks, including up to nine visits at a local study site. Receive a total of 12 weeks of daily study drug dosing. After completing 12 weeks of study drug dosing, attend all follow-up visits required by the study physician.
For more information, please call (513) 536-0707 or visit https://www.tforcegold.com/ or view https://www.youtube.com/watch?v=LgJP5uzDj2I
Do you have angry outbursts? Are you easily irritated? Do you have a “short fuse?”
What
Those terms can be associated with a disorder called Intermittent Explosive Disorder (IED). You may qualify to participate in a research study that will gather information about the side effects of an investigational medication on the symptoms of IED.
Who
18-65 year old men and women who have repeated, sudden episodes of impulsive, aggressive, violent behavior or angry verbal outbursts in which they react grossly out of proportion to the situation. This reaction seems more angry or aggressive than how most other people would have reacted in the same situation.
Pay
Study-related evaluations, tests and medication without charge. Eligible participants will be compensated up to $75 per visit for their time and travel.
Details
For more information, contact Morgan at (513) 536-0700 or morgan.pond@lindnercenter.org