Current Clinical Trials

Research studies at the Research Institute at Lindner Center of HOPE are currently being conducted for Bipolar Disorder, Major Depression and Eating Disorders.

The Research Institute at Lindner Center of HOPE conducts research regarding the biological causes and treatments for mood and eating disorders. Currently Dr. Susan McElroy is recruiting people for studies on bipolar disorder (also known as manic depression), major depression, eating disorders (binge eating disorder), and smoking cessation.


For more information about the Research Institute, contact (513) 536-0716 or click here.

Currently Dr. Susan McElroy is recruiting people for studies on bipolar disorder (also known as manic depression), major depression, eating disorders (binge eating disorder), and smoking cessation. 


If you would like to fill out a short pre-screen questionnaire for our depression study, please click here.

Bipolar Biobank for Genetic Research

Do you have Bipolar Disorder and want to help further research?
Become part of the bipolar Biobank.

What: 
In partnership with the Mayo Clinic, researchers at the Lindner Center of HOPE are developing a research resource for bipolar disorder called a Biobank.  Participants in this Biopolar Biobank provide samples of blood, complete and interview and questionnaires, and allow access to medical records.  The Bipolar Biobank will make it much easier to conduct research studies about bipolar disorder because researchers will have access to blood samples, along with patient data from thousands of people, all in one place.

Who:
Adults 18-80 years old who have been diagnosed with bipolar type 1 or 2 disorder, or schizoaffective disorder (bipolar type) may be eligible to participate.

Pay:
Participants will be reimbursed $50 for their time spent completing the entire study.

There is a one-time interview and blood donation required. Read more about it, click here.

For more information, please call (513) 536-0707.


Do you have bipolar disorder and are you currently feeling depressed

What: 
This research study will compare and evaluate the response and side effects of two investigational medications for people with bipolar I or II, or people with schizoaffective
bipolar depression. The study will last 16 weeks and participants will be reimbursed for time and travel.

Who:
Adults ages 18 to 65 who have been diagnosed with bipolar type I or II disorder, or schizoaffective bipolar depression may be eligible to participate.

Pay:
Participants get paid $50 at the first visit of the study and $50 at the end of the study (at week 16).  A total of $100.

Read more about it, click here.

For more information, please call (513) 536-0707.


Are you currently suffering from depression?

What: 
The Lindner Center of HOPE is conducting a research study that will evaluate people in a current depressive episode. Participants will be treated under the direction of their doctor and provide 3 blood samples during the study. The purpose of the study is to examine if unipolar depression, bipolar I or bipolar II depression can be determined from a blood sample. The study will last 9 weeks (6 visits during that time). Participants will receive treatment from their regular doctor and not from the study.

Who:
Adults 18 to 70 who have been diagnosed with major depression, bipolar type I or II disorder and currently depressed may be eligible to participate.

Pay:
Participants will be reimbursed for time and travel to the Lindner Center of Hope (Mason, OH). You will be compensated $50 for the screening visit, $100 for completing the initial baseline visit and $50 for each subsequent study visit, for a maximum total of $350 if you complete all of the study visits.

Read more about it, click here.

For more information, please call (513) 536-0707.


Are your Bipolar medications working well, but you’re struggling with being overweight?

What :
The Lindner Center of HOPE is conducting a clinical trial with an FDA-approved antiobesity medication, seeking patients with bipolar disorder who are interested in losing weight.

Who :
Overweight or obese adults, 18-65yrs of age inclusive, who have been diagnosed with and are on stable medication regimen for their bipolar disorder

Pay:
Participants receive $50/visit. Nutritional & lifestyle counseling, lab and diagnostic tests provided free of charge.

For more information, please call (513) 536-0710


For more information about the Research Institute, contact (513) 536-0716 or email Brian Martens at brian.martens@lindnercenter.org.

Do you want to quit smoking?

Lindner Center of HOPE is conducting a clinical trial of a non‐invasive, investigational medical device, Deep Transcranial Magnetic Stimulation, that may help people to quit smoking.

To be eligible you must:

  • Be between the ages of 22– 70 years old
  • Have smoked at least 10 cigarettes a day for over a year
  • Want to quit smoking

All qualified participants will receive study related exams, lab work and treatments at no cost.
Enrolled participants will receive compensation for time and travel.

For more information, please call Anna at (513) 536-0721.

 

 


For more information about the Research Institute, contact (513) 536-0716 or click here.

Are you currently suffering from depression?

What: 
The Lindner Center of HOPE is conducting a research study that will evaluate people in a current depressive episode. Participants will be treated under the direction of their doctor and provide 3 blood samples during the study. The purpose of the study is to examine if unipolar depression, bipolar I or bipolar II depression can be determined from a blood sample. The study will last 9 weeks (6 visits during that time). Participants will receive treatment from their regular doctor and not from the study.

Who:
Adults 18 to 70 who have been diagnosed with major depression, bipolar type I or II disorder and currently depressed may be eligible to participate.

Pay:
Participants will be reimbursed for time and travel to the Lindner Center of Hope (Mason, OH). You will be compensated $50 for the screening visit, $100 for completing the initial baseline visit and $50 for each subsequent study visit, for a maximum total of $350 if you complete all of the study visits.

Read more about it, click here.

For more information, please call (513) 536-0707.


Taking depression medication but still feeling depressed? 

 What : Rapastinel/ RAP-MD

The Lindner Center of HOPE is conducting a clinical trial of Rapastinel, a novel experimental drug, to be used in addition to conventional medication in the treatment of Major Depression.  Rapastinel has received FDA designation as a “breakthrough therapy” with individuals whose symptoms haven’t experienced significant improvement from their current antidepressant.

Who:

Adults 18-65yrs of age inclusive who are currently depressed and are taking an antidepressant medication with not sufficient improvement

 Pay:

Participants receive $75/visit and are expected to come for 12 study visits. Lab and diagnostic tests provided free of charge

For more information, please call (513) 536-0710


If interested in participating in the trial, contact 513-536-0710.